Protein Details: Aquaporin AqpM

Protein ID

ICDB_Pro_0200

Protein Name

Aquaporin AqpM

Gene Name

aqpM; MTH_103

Organism

Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)

Length

246 amino acids

AlphaFoldDB

AF-O26206-F1-model_v4.pdb

Function

Channel that permits osmotically driven movement of water in both directions. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity. Exhibits also a transient but reproducible increase in the initial glycerol flux (By similarity).

Sequence

MVSLTKRCIAEFIGTFFLVFFGAGAAAITLMIASGGTAPNPFNIGIGLLGGLGDWVAIGLAFGFAIAASIYALGNISGCHINPAVTIGLWSVKKFPGRDVVPYIIAQLLGAAFASFIFLQCAGITAATIGGLGATAPFPGIGYWQAMLAETVGTFLLMITIMGIAVDERAPKGFAGIIIGLTVAGIITTIGNITGSSLNPARTFGPYLNDMVFAGTNLWNYFPIYVIGPVVGAVLAALTYQYLTSE

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1128/jb.179.22.7135-7155.1997

RefSeq

WP_010875742.1

Feature